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Limitations and responsible use

  • The implementation targets static, baseline-covariate prediction.
  • It returns one RMST prediction per chosen horizon, not a coherent full curve.
  • The marginal Kaplan-Meier pseudo-observation construction requires stronger censoring assumptions than conditional independence given covariates.
  • Predictions are prognostic, not causal. They do not estimate treatment effects or justify treatment selection.
  • Grouped agreement and discrimination do not establish individual calibration or clinical deployment utility.
  • Hosted backbones transfer processed data to third-party infrastructure.
  • Foundation-model packages and checkpoints evolve; reproducibility requires explicit version and checkpoint pinning.

Use independent validation, censoring-support diagnostics and a prespecified horizon before any disease-specific application. Prospective validation and institutional review are required before clinical use.